Jennifer Guo, MD, PhD

Director of Psychedelic Medicine

Dr. Guo is a psychiatrist whose focus is in treating patients with depression, anxiety, bipolar disorder, and other psychiatric disorders. Her primary goal as a clinician is to help patients remove the impediment of psychiatric symptoms and emotional roadblocks to live full and flourishing lives.

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More about Jennifer Guo, MD, PhD

Jennifer Guo is passionate about connecting with her patients first and foremost. She works with them to design a comprehensive treatment plan to target their symptoms and improve their overall sense of well-being. Her style with patients is highly collaborative, and she meets patients where they are at each stage of their journey to wellness. Jennifer appreciates patients with an openness to self-discovery and exploration, and works to ensure they feel heard and are engaged in their treatment.

She is particularly interested in using interventional psychiatric approaches including Transcranial Magnetic Stimulation (TMS) and esketamine for treatment-resistant depression. She sees TMS as a non-invasive, durable, and modern treatment for psychiatric disorders with minimal side effects, allowing providers to modulate specific brain circuitry involved in these disorders in a targeted way.

Jennifer Guo joined Mindful Health Solutions in the Fall of 2019.

Personal Interests

Dr. Guo loves exploring the natural beauty of the Bay Area and its surroundings. She enjoys food and often tries to take advantage of the rich restaurant scene in the Bay Area. She is an avid reader, enjoys traveling, and most of all, likes spending time with friends and family.

Education & Experience

Dr. Guo received a joint bachelor’s and master’s degree in Neuroscience from John Hopkins University, where she graduated with honors. She attended the Yale University School of Medicine and received her Doctor of Medicine and PhD in Neuroscience. She became interested in psychiatry as a medical student after seeing how much patients can be affected by mental illness and how the right treatments can improve symptoms. Psychiatry allowed her to combine her passion for patients’ stories with her interest in neurobiology.

She completed her psychiatry residence at the University of California, San Francisco (UCSF). She was the Chief Resident of the UCSF Psychiatry Adult Inpatient Program, where she gained additional clinical, teaching, and administrative experience. She was the senior resident in the Depression Clinic where she became particularly interested in treatment-resistant depression. She received advanced training in TMS, ketamine, and ECT at UCSF, and graduated with an Area of Distinction in Interventional Psychiatry. She also completed the Psychoanalytic Psychotherapy Training Program through the San Francisco Center for Psychoanalysis. She continues to teach and mentor residents as a volunteer clinical professor in the Department of Psychiatry at UCSF.

Certifications & Memberships

  • UCSF, Clinical Professor
  • Member, American Psychiatric Association
  • Member, Northern California Psychiatric Society
  • Member, Clinical TMS Society
  • San Francisco Psychoanalytic Psychotherapy Training Program
  • Interventional Psychiatry Area of Distinction, UCSF


Buzza C, Fiskin A, Breur J, Guo JN, Izenberg J, Kamholz B, Hung E, Acharya A. Competencies for Global Mental Health: Developing Training Objectives for a Post-Graduate Fellowship for Psychiatrists. Ann Global Health. 2018; 84:717–26.

Guo JN, Kim R, Chen Y, Negishi M, Jhun S, Weiss S, Ryu J, Bai X, Xiao W, Feeney, E, Rodriguez- Fernandez J, Mistry H, Crunelli V, Crowley MJ, Mayes LC, Constable RT, Blumenfeld H. Impaired consciousness in patients with absence seizures investigated by functional MRI, EEG, and behavioural measures: a cross-sectional study. Lancet Neurology. 2016;15:1336-45.

Guo JN, Kothari J, Leckman JF, Ostroff R. Successful treatment of Tourette’s syndrome with ECT: a case report. Biol Psychiatry. 2014; pii: S0006-3223(14)00743-4.

Killory B, Bai X, Negishi M, Vega C, Spann MN, Vestal M, Guo JN, Berman R, Danielson N, Trejo G, Shisler D, Novotny EJ, Constable RT, Blumenfeld H. Impaired attention and network connectivity in childhood absence epilepsy. Neuroimage. 2011;56(4):2209-17.

Danielson N, Guo JN, Blumenfeld H. The default mode network in epilepsy. Behavioural Neurology. 2011; 24(1):55-65.

Vega C, Guo JN, Killory B, Danielson N, Vestal M, Berman R, Martin L, Gonzalez JL, Blumenfeld H, Spann MN. Symptoms of anxiety and depression in childhood absence epilepsy. Epilepsia. 2010;19(1):82-5.

Guo JN, Blumenfeld H. (2014). Network Imaging. In C Faingold and H Blumenfeld (Eds.), Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics. New York: Elsevier.

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