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Kristina Circelli
Director of Marketing
kcircelli@mymhs.com

Introducing MindfulONE – Mindful Health Solutions Acquires Breakthrough Technology for Same-Day TMS Treatment

San Francisco, CA (June 24, 2025) — �� Mindful Health Solutions is proud to announce the implementation of MindfulONE, a next-generation depression treatment protocol that delivers rapid, durable relief in just one day — ��a dramatic leap forward from the traditional 36-day rTMS treatment course. 

MindfulONE pushes the frontiers of depression therapy, eliminating the burden of time constraints, travel demands, work schedules, and other limitations by condensing weeks of therapy into a single day. Most patients experience full treatment effects within 1 to 6 weeks, up to and including full remission of depression. In fact, 70% of patients experience full remission with this revolutionary protocol. 

“MindfulONE marks a major step in advancing interventional psychiatry,” said Dr. Tobias Marton, CMO of Mindful Health Solutions. “It brings new hope to patients by combining speed, safety, and sustained efficacy in a way that transforms how we treat mood disorders, including both unipolar and bipolar depression.” 

How MindfulONE Works
MindfulONE combines a one-time, pre-treatment dose of two safe medications to prepare the brain for change, followed by 20 brief stimulation sessions administered over the course of a single day. Accelerated TMS is proven safe and effective, administered as an outpatient procedure at our San Francisco clinic. 

What is Transcranial Magnetic Stimulation?
Transcranial Magnetic Stimulation (TMS) was FDA-approved in 2008 as an alternative interventional psychiatric treatment for Major Depressive Disorder (MDD) and Treatment-Resistant Depression (TRD), as well as related mood and anxiety disorders. During treatment, TMS coils deliver highly targeted, localized electromagnetic pulses to areas of the brain with reduced electrical activity, stimulating the release of neurotransmitters and hormones such as serotonin and dopamine. Once these neurons are stimulated by TMS, they continue to release neurotransmitters for a longer period of time compared to other treatments like antidepressants. 

At Mindful Health Solutions, we understand the devastating hold depression takes on a person, and how overwhelming the thought of ongoing treatment can feel. MindfulONE is the solution. Learn more about this innovative treatment and how to book a session here. 

About Mindful Health Solutions
Mindful Health Solutions is one of the nation’s leading providers of innovative behavioral health care and is the second-largest administrator of SPRAVATO (esketamine) in the nation. At all times, we remain focused on cutting-edge interventional psychiatric research and treatment protocols such as TMS, SPRAVATO (esketamine), and IV Ketamine Therapy for patients struggling with treatment-resistant depression and other psychiatric illnesses. Our experienced clinical team is dedicated to applying groundbreaking therapies supported by positive outcome data, academic rigor, and years of expertise in novel therapeutics. Outpatient clinics are located in California, Georgia, Texas, and Washington. Learn more via our website.